1712-1770. Politician, Prime Minster and father of Nugent Buckingham. 

George Grenville by education and temperament appears to have possessed characteristics as divergent as the poles from those most conspicuous in his wife’s forebears. He was well embarked on his political career at the time of his marriage, having abandoned the Law in 1741 and entered Parliament in accordance with the wishes of his maternal uncle, Viscount Cobham. His reputation in thirty years of political life, during which he attained to the highest positions possible to an English statesman, is well-known. History deals unsympathetically with the man to whose narrowness of outlook maybe attributed the War of American Independence, but though he possessed hardly a single quality for a successful administrator, he was a man of unbounded industry and highmindedness He sprang on both sides from men who for generations had spent their lives in public service-through his father, from the ancient line of the Grenvilles of Wotton, and through his mother from the Temples of Stowe. (Leighton)

• Born in Westminster, London on 14 October 1712
• Educated at Eton and Christ Church, Oxford
• Entered Inner Temple and Lincoln's Inn and called to the Bar in 1735
• Entered parliament in 1741
• Lord of the Admiralty: 27 December 1744 to June 1747
• Lord of the Treasury: June 1747 to March 1754
• Married Elizabeth Wyndham in 1749; 8 children
• Treasurer of the Navy: March 1754 to 20 November 1755; November 1756 to 9 April 1757; June 1757 to May 1762
• Leader of the House of Commons: October 1761 to October 1762; April 1763 to July 1765
• Secretary of State, Northern Department; 27 May to 9 October 1762
• First Lord of the Admiralty; October 1762 to April 1763
• First Lord Commissioner of the Treasury (Prime Minister) and Chancellor of the Exchequer: 16 April 1763 to 10 July 1765
• Died in Bolton Street, London on 13 November 1770.

His nickname was the "Gentle Shepherd." This arose from a speech on the cider tax in 1763 in which he repeatedly asked where else a tax could be laid. Opposition MPs began to sing the hymn, "Gentle Shepherd, Tell Me Where."

He was, however, admired by Burke:

His character was thus drawn by Burke, in his speech on American Taxation (1774):—“Undoubtedly Mr Grenville was a first-rate figure in this country; with a masculine understanding and a stout and resolute heart, he had an application undissipated and unwearied. He took public business not only as a duty he was to fulfil, but as a pleasure he was to enjoy; and he seemed to have no delight out of this house, except in such things that in some way related to the business that was to be done within it. If he was ambitious, I will say this for him, his ambition was of a noble and generous strain. It was to raise himself, not by the low pimping of a court, but to win his way to power though the laborious gradations of public service; and to secure himself a well-earned rank in Parliament, by a through knowledge of its constitution, and a perfect practice of all its business.” {Stowe 1848 Catalogue]